And it showed the study Conducted by researchers from the University College of Medicine Washington in “saint louis” That there is a vital path between Brain andTissue Fat in the body plays an essential role in regulating energy production and directly affects the aging process.
A feedback loop between the brain and fat
Researchers have revealed a feedback loop between the brain and body fat, a process that contributes to maintaining the body’s internal balance and plays an essential role in energy regulation.
The results showed that this link weakens with age, leading to an imbalance in the molecular and electrical signals that ensure the organs function properly.
The study in the journal “Cell Metabolism”
The study was published in the prestigious journal Cell Metabolism, and delved into the understanding of the biological process that regulates lifespan.
Researchers studied the effect of this episode on… Laboratory miceThey discovered that stimulating specific neurons in a specific area of the brain – called the ventromedial hypothalamus – can improve the body’s energy production process.
Exciting experience
In the team’s experiment, scientists genetically modified mice so that the neural pathway between the brain and fat remained active even after the mice reached advanced age.
The results were astonishing: these mice showed greater physical activity, delayed signs of aging, and lived longer than mice in which this pathway was not activated.
Scientific explanation
When these neurons in the brain are activated, signals are sent to adipose tissue to stimulate it to release energy, thus providing cellular fuel for physical activity.
Adipose tissue also secretes an important protein called eNAMPT, which returns to the brain, further stimulating its functions.
Announcement of discovery by researchers
Dr. Shin-ichiro Imai, the lead author of the study, explained that this discovery is a major development in the field of aging research, especially since attempts to extend lifespan in previous studies were limited to simpler organisms such as worms and flies.
These findings open new horizons in the fields of medicine and research on how to influence the aging process, which may lead to the development of ways to preserve this important neural pathway as people age and thus slow the effects of aging.
This study may be a turning point towards a deeper understanding of how the brain affects our health and longevity, and offers hope for finding ways to protect the health of our brains and bodies for as long as possible.
